Immunoglobulin Idiotype

《英文msh詞典》Immunoglobulin Idiotype
[入口詞] Immunoglobulin Idiotype
[主題詞] Immunoglobulin Idiotypes
[英文釋義] Unique,genetically controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g.,another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.